CBR3 and SHOX2

		CBR3	SHOX2
Description		carbonyl reductase 3	short stature homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytosol	Chromatin Nucleus
	Molecular Function	3-keto Sterol Reductase Activity Carbonyl Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity NADPH Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Osteoblast Differentiation Regulation Of Heart Rate Positive Regulation Of Mesenchymal Cell Proliferation Chondrocyte Development Sinoatrial Node Development Sinoatrial Valve Development Cardiac Right Atrium Morphogenesis Regulation Of Transcription By RNA Polymerase II Nervous System Development Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Axonogenesis Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis Muscle Tissue Morphogenesis Cardiac Pacemaker Cell Differentiation Sinoatrial Node Cell Development Regulation Of Branching Morphogenesis Of A Nerve
Pathways		Phase I - Functionalization of compounds
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Lumbar spine bone mineral density ( 22504420)	Body mass index ( 26426971) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 25429064 23563607 31562340) Idiopathic dilated cardiomyopathy ( 29495422) Lung cancer in never smokers ( 28604730) Monobrow ( 27182965) Neurociticism ( 29500382) Neuroticism ( 29255261) Pulse pressure ( 30224653)
Interacting Genes		15 interacting genes: ANK1 ARIH2 ATP5PO BICD2 CLU IL10RB ITSN1 KCNE1 KCNJ15 PCP4 RAB35 RCAN1 SDCBP SHOX2 UBC	5 interacting genes: CBR3 CDK4 KDR TRIM29 ZDHHC17
Entrez ID		874	6474
HPRD ID		07222	03936
Ensembl ID		ENSG00000159231	ENSG00000168779
Uniprot IDs		O75828 V9HW40	A6NLG4 O60902
PDB IDs		2HRB
Enriched GO Terms of Interacting Partners?
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