CBR3 and KCNJ15

		CBR3	KCNJ15
Description		carbonyl reductase 3	potassium inwardly rectifying channel subfamily J member 15
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytosol	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	3-keto Sterol Reductase Activity Carbonyl Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity NADPH Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Phase I - Functionalization of compounds	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine Butamben
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Lumbar spine bone mineral density ( 22504420)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Body shape index ( 34021172) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Metabolite levels ( 23823483) Monocyte count ( 32888494) Non-response to antidepressants and depression ( 27622933) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		15 interacting genes: ANK1 ARIH2 ATP5PO BICD2 CLU IL10RB ITSN1 KCNE1 KCNJ15 PCP4 RAB35 RCAN1 SDCBP SHOX2 UBC	16 interacting genes: CBR3 CTSE DSCAM IL16 KCNE1 KCNJ16 KCNJ2 KCNJ5 LRP8 MTCH1 PATJ SLC39A2 SNTA1 SON TOR1B TTC3
Entrez ID		874	3772
HPRD ID		07222	03659
Ensembl ID		ENSG00000159231	ENSG00000157551
Uniprot IDs		O75828 V9HW40	Q99712
PDB IDs		2HRB
Enriched GO Terms of Interacting Partners?
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