STK16 and MIER3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STK16	MIER3
Description		serine/threonine kinase 16	MIER family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Transcription Corepressor Activity Histone Deacetylase Activity Histone Deacetylase Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation
Pathways
Drugs		Fostamatinib
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Brain morphology (MOSTest) ( 32665545) Breast cancer ( 31757997) Cortical surface area (MOSTest) ( 32665545) Fasting plasma glucose ( 32682390) Subcortical volume (MOSTest) ( 32665545) Waist circumference ( 28552196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		85 interacting genes: ADAMTSL4 AGR2 ARNT2 ATP23 BHLHA9 CALCOCO2 CBX3 CCDC33 CFP CRX CSKMT CSNK2B CYSRT1 DDIT4L DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 FRS3 FXR1 GABPA IKZF3 INCA1 KCTD14 KCTD17 KLHL20 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP26-1 KRTAP6-3 MBP MEOX2 MGAT5B MIER3 MIIP MTUS2 NAA80 NAGK NBPF19 NIF3L1 NOTCH2NLA PCSK5 PKNOX2 PLA2G10 PLSCR1 PLSCR3 PRDM6 PRKAR1B PTH1R REL RFX6 RPIA RSPO4 SAXO1 SKIL SOCS2 SPRY2 SSC4D TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6 TUBA4A USP54 YPEL3 ZMAT1 ZNF330 ZNF343 ZNF774	2 interacting genes: MCRS1 STK16
Entrez ID		8576	166968
HPRD ID		05281	08199
Ensembl ID		ENSG00000115661	ENSG00000155545
Uniprot IDs		B4DPS1 B8ZZI5 O75716	Q7Z3K6
PDB IDs		2BUJ
Enriched GO Terms of Interacting Partners?
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