STK16 and TRAF3IP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		STK16	TRAF3IP2
Description		serine/threonine kinase 16	TRAF3 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Cellular_component Cytoplasmic Vesicle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Signaling Receptor Binding Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus	Establishment Of T Cell Polarity B Cell Homeostasis B Cell Apoptotic Process Kidney Development Positive Regulation Of Defense Response To Virus By Host Leukocyte Activation Involved In Inflammatory Response Transitional Two Stage B Cell Differentiation B Cell Affinity Maturation Eosinophil Mediated Immunity Protein Import Into Nucleus Inflammatory Response Humoral Immune Response Heart Development Response To Xenobiotic Stimulus Signal Transduction Involved In Regulation Of Gene Expression CD40 Signaling Pathway T Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Intracellular Signal Transduction Interleukin-17A-mediated Signaling Pathway Type 2 Immune Response Neutrophil Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Skin Development MRNA Stabilization Lymph Node Development Spleen Development Mucus Secretion Protein K63-linked Ubiquitination T-helper 17 Type Immune Response Interleukin-17-mediated Signaling Pathway Protein Localization To P-body Eosinophil Homeostasis
Pathways
Drugs		Fostamatinib
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Intraocular pressure ( 29617998) Psoriasis ( 25903422 20953188 20953190 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624 20953186) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258) Ulcerative colitis ( 28067908)
Interacting Genes		85 interacting genes: ADAMTSL4 AGR2 ARNT2 ATP23 BHLHA9 CALCOCO2 CBX3 CCDC33 CFP CRX CSKMT CSNK2B CYSRT1 DDIT4L DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 FRS3 FXR1 GABPA IKZF3 INCA1 KCTD14 KCTD17 KLHL20 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP26-1 KRTAP6-3 MBP MEOX2 MGAT5B MIER3 MIIP MTUS2 NAA80 NAGK NBPF19 NIF3L1 NOTCH2NLA PCSK5 PKNOX2 PLA2G10 PLSCR1 PLSCR3 PRDM6 PRKAR1B PTH1R REL RFX6 RPIA RSPO4 SAXO1 SKIL SOCS2 SPRY2 SSC4D TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6 TUBA4A USP54 YPEL3 ZMAT1 ZNF330 ZNF343 ZNF774	23 interacting genes: CD40 CHUK FHL3 GOLGA2 HSD17B10 IKBKB IKBKG MAP3K7 MDFI MRPL28 RIMBP3 STK16 TBK1 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 TRIM55 TRIM63 TRIP6 UBC UBE2V1
Entrez ID		8576	10758
HPRD ID		05281	06129
Ensembl ID		ENSG00000115661	ENSG00000056972
Uniprot IDs		B4DPS1 B8ZZI5 O75716	O43734
PDB IDs		2BUJ
Enriched GO Terms of Interacting Partners?
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