AP3B1 and RNGTT

		AP3B1	RNGTT
Description		adaptor related protein complex 3 subunit beta 1	RNA guanylyltransferase and 5'-phosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding	MRNA Guanylyltransferase Activity Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding ATP Binding GTP Binding Protein Tyrosine/serine/threonine Phosphatase Activity RNA Guanylyltransferase Activity Triphosphatase Activity
	Biological Process	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development	7-methylguanosine MRNA Capping RNA Processing Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF1 fusions	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection mRNA Capping RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Insulin resistance/response ( 21901158) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Serum alkaline phosphatase levels ( 33547301) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)	Colorectal or endometrial cancer ( 26621817) Depression in smokers ( 30219690) Graft survival time in renal transplantation (donor effect) ( 32080893) Height ( 31562340) Response to statin therapy ( 20339536) Simvastatin-induced myopathy ( 31220337) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		19 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 CXADR FCGR2B GKAP1 RNGTT SLC30A3 SSBP2 ZER1	3 interacting genes: AP3B1 APPBP2 RNMT
Entrez ID		8546	8732
HPRD ID		04551	04621
Ensembl ID		ENSG00000132842	ENSG00000111880
Uniprot IDs		A0A0S2Z5J4 O00203	B4DSJ8 O60942 Q7Z3R6
PDB IDs			2C46 3S24
Enriched GO Terms of Interacting Partners?
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