GEMIN2 and SNRPD1

Number of citations of the paper that reports this interaction (PubMedID 11389857)
129

Data Source:
HPRD (in vivo, in vitro)

		GEMIN2	SNRPD1
Description		gem nuclear organelle associated protein 2	small nuclear ribonucleoprotein D1 polypeptide
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Commitment Complex Nucleus Nucleoplasm U5 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding U1 SnRNP Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Negative Regulation Of RNA Binding	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing
Pathways		snRNP Assembly	snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Vitamin D levels ( 28757204)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		34 interacting genes: AKAP6 BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	18 interacting genes: CLNS1A DDX20 ERCC6 GEMIN2 GEMIN4 GEMIN5 IL7R LSM3 LSM8 PRMT5 PTEN SMN1 SMN2 SNRPB SNRPD2 SREK1 U2AF1 WDR77
Entrez ID		8487	6632
HPRD ID		03999	03040
Ensembl ID		ENSG00000092208	ENSG00000167088
Uniprot IDs		O14893	P62314
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y
Enriched GO Terms of Interacting Partners?
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