GEMIN2 and HOXD10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GEMIN2	HOXD10
Description		gem nuclear organelle associated protein 2	homeobox D10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Chromatin Nucleus Nucleoplasm Cytosol Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Negative Regulation Of RNA Binding	Regulation Of Transcription By RNA Polymerase II Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Spinal Cord Motor Neuron Cell Fate Specification Embryonic Limb Morphogenesis Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Peripheral Nervous System Neuron Development Neuromuscular Process
Pathways		snRNP Assembly
Drugs
Diseases
GWAS		Vitamin D levels ( 28757204)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462) Kidney volume ( 34128465) Male-pattern baldness ( 28196072)
Interacting Genes		34 interacting genes: AKAP6 BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	7 interacting genes: CREBBP EP300 GEMIN2 GMNN HMGB1 PBX1 RCHY1
Entrez ID		8487	3236
HPRD ID		03999	00867
Ensembl ID		ENSG00000092208	ENSG00000128710
Uniprot IDs		O14893	P28358
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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