SUPT3H and PYGO2

Number of citations of the paper that reports this interaction (PubMedID 20937768)
28

Data Source:
BioGRID (pull down)

		SUPT3H	PYGO2
Description		SPT3 homolog, SAGA and STAGA complex component	pygopus family PHD finger 2
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFTC Complex	Nucleoplasm Beta-catenin-TCF Complex
	Molecular Function	Transcription Coactivator Activity Protein Heterodimerization Activity	Chromatin Binding Protein Binding Histone Acetyltransferase Regulator Activity Histone Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Histone Deubiquitination Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated	Kidney Development Lens Development In Camera-type Eye Spermatid Nucleus Differentiation Brain Development Mammary Gland Development Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Histone Acetylation Positive Regulation Of Chromatin Binding Developmental Growth Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Canonical Wnt Signaling Pathway
Pathways		HATs acetylate histones	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		ADAMTS13 activity ( 25934476) Attention deficit hyperactivity disorder ( 18839057) Chin dimples ( 27182965) Estimated glomerular filtration rate ( 31152163) facial morphology traits (multivariate analysis) ( 27193062) Glaucoma ( 31959993) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 25282103 25429064 19893584 23563607 31562340 18391951) Hip circumference adjusted for BMI ( 34021172) Hip minimal joint space width ( 27701424) Intraocular pressure ( 31959993 30054594) Large artery stroke ( 24262325) Lumbar spine bone mineral density ( 22504420) Lymphocyte counts ( 32888494) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Nose size ( 27182965) Obesity-related traits ( 23251661) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Osteoarthritis of the hip or knee ( 30664745) Post bronchodilator FEV1/FVC ratio ( 26634245) Serum alkaline phosphatase levels ( 33547301) Stroke (ischemic) ( 22941190) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Waist circumference adjusted for body mass index ( 34021172)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		5 interacting genes: DDB1 H3-4 MYC PYGO2 TCF3	7 interacting genes: AKT1 BCL9 DCAF1 KAT2A NF2 SUPT3H TRRAP
Entrez ID		8464	90780
HPRD ID		04254	06065
Ensembl ID		ENSG00000196284	ENSG00000163348
Uniprot IDs		A0A024RD67 B4E1H0 O75486	Q5T170 Q9BRQ0
PDB IDs			2XB1 4UP0 4UP5
Enriched GO Terms of Interacting Partners?
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