PARD6B and TRIM35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PARD6B	TRIM35
Description		par-6 family cell polarity regulator beta	tripartite motif containing 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	Protein Kinase C Binding Protein Binding	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell
Pathways		Tight junction interactions RHOV GTPase cycle	Interferon gamma signaling
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)	Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)
Interacting Genes		34 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB OGT PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4	49 interacting genes: ADIPOQ BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410
Entrez ID		84612	23087
HPRD ID		18703	15553
Ensembl ID		ENSG00000124171	ENSG00000104228
Uniprot IDs		Q9BYG5	E5RGB3 Q9UPQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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