TRIM35 and PARD6B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM35	PARD6B
Description		tripartite motif containing 35	par-6 family cell polarity regulator beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Kinase C Binding Protein Binding
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly
Pathways		Interferon gamma signaling	Tight junction interactions RHOV GTPase cycle
Drugs
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)	Bipolar disorder ( 21771265)
Interacting Genes		49 interacting genes: ADIPOQ BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410	34 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB OGT PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4
Entrez ID		23087	84612
HPRD ID		15553	18703
Ensembl ID		ENSG00000104228	ENSG00000124171
Uniprot IDs		E5RGB3 Q9UPQ4	Q9BYG5
PDB IDs
Enriched GO Terms of Interacting Partners?
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