JAGN1 and FIS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		JAGN1	FIS1
Description		jagunal homolog 1	fission, mitochondrial 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Mitochondrion Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Cytosol Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Neutrophil Mediated Immunity Exocytosis Endoplasmic Reticulum Organization Protein Transport Vesicle-mediated Transport Neutrophil Differentiation Granulocyte Colony-stimulating Factor Signaling Pathway Defense Response To Fungus Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Tunicamycin Neutrophil Migration	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Response To Muscle Activity Peroxisome Fission Response To Nutrient Levels Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Cellular Response To Glucose Stimulus Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Cellular Response To Toxic Substance Cellular Response To Peptide Response To Fluoride Negative Regulation Of ATP Metabolic Process Cellular Response To Thapsigargin Response To Flavonoid Response To Hypobaric Hypoxia Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS			Rheumatoid arthritis ( 30891314)
Interacting Genes		126 interacting genes: AGPAT4 APP AQP6 ARL13B BCL2L13 BET1 BMP10 BNIP1 BNIP3 BSND BTNL9 C4orf3 CALHM6 CCL4L2 CD79A CDIPT CERS4 CGRRF1 CLDN7 CLEC12B CLEC4D CLEC7A CMTM5 COX20 CREB3L1 CYBC1 CYP4F2 DNAJC30 EBP EDA2R EHHADH ELOVL4 ERG28 ERGIC3 F11R FAM177A1 FAM209A FCGR1A FCRL2 FCRL4 FDFT1 FIS1 FKBP8 FNDC9 FRMD3 FXYD6 GIMAP1 GIMAP5 GJB5 GOLM1 GOSR2 GP2 GPR152 GPR37L1 HMOX1 HSD17B13 HTATIP2 ICMT IER3IP1 IFNGR2 IL3RA KASH5 KCNA1 KIR2DL3 KIR3DL3 LEMD1 LHFPL5 LMNA LPAR3 MFF MRM3 MTIF3 NINJ2 NRG1 OTULINL PDZK1IP1 PLP1 PLPP2 PSCA RETREG3 RTP2 SACM1L SAR1A SCD SEC22B SERP1 SLAMF6 SLC16A2 SLC23A2 SLC34A2 SMAGP SMIM1 SMIM19 STOML3 STX1A STX3 STX5 STX7 STX8 TECR TIMM23 TMEM100 TMEM106C TMEM120B TMEM128 TMEM14B TMEM199 TMEM207 TMEM237 TMEM242 TMEM243 TMEM52B TMEM65 TMIE TNFSF14 TREX1 TSNARE1 UBE2J1 USE1 VAMP2 VAMP5 VAPA VAPB VKORC1 VSIG4 VTI1B	31 interacting genes: A2M ABHD6 APH1A BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 KMT2E MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1
Entrez ID		84522	51024
HPRD ID		13749	12352
Ensembl ID		ENSG00000171135	ENSG00000214253
Uniprot IDs		Q8N5M9	Q9Y3D6
PDB IDs		6WVD	1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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