RPAIN and CLNK

Number of citations of the paper that reports this interaction (PubMedID 25814554)
26

Data Source:
BioGRID (two hybrid)

		RPAIN	CLNK
Description		RPA interacting protein	cytokine dependent hematopoietic cell linker
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm PML Body	Cytoplasm Protein-containing Complex Mast Cell Granule
	Molecular Function	Protein Binding Protein-containing Complex Binding Metal Ion Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	DNA-dependent DNA Replication DNA Repair DNA Recombination Protein Import Into Nucleus	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 29273807) Menopause (age at onset) ( 26414677) Neutrophil count ( 32888494) White blood cell count ( 32888494)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Gout ( 33832965) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		7 interacting genes: ADH6 CDCA5 CLNK CYP17A1 GSTA1 RAD51B TNS4	30 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD JAKMIP1 LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		84268	116449
HPRD ID		14615	14720
Ensembl ID		ENSG00000129197	ENSG00000109684
Uniprot IDs		B3KTT3 Q86UA6	Q7Z7G1
PDB IDs
Enriched GO Terms of Interacting Partners?
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