ZMYND12 and TSEN54

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZMYND12	TSEN54
Description		zinc finger MYND-type containing 12	tRNA splicing endonuclease subunit 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process		TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing
Pathways			tRNA processing in the nucleus
Drugs
Diseases
GWAS			Deep white matter hyperintensities ( 32517579) FEV1 ( 30804560) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Platelet count ( 32888494) Plateletcrit ( 32888494) Sight-threatening diabetic retinopathy in type 2 diabetes ( 26188370)
Interacting Genes		81 interacting genes: ABI2 ARHGAP8 ARMC8 ARNTL C1orf109 C1orf50 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM214B FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PPP1R32 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	21 interacting genes: BRCA1 CCDC57 CLP1 CSNK2B GOLGA6L9 IRF4 KPNA5 KRT31 LHX3 LHX4 LMO2 MCPH1 MRPL38 NAA10 NCKIPSD NFKBID RINT1 TRIM23 TRIML2 TSEN2 ZMYND12
Entrez ID		84217	283989
HPRD ID		15740	12291
Ensembl ID		ENSG00000066185	ENSG00000182173
Uniprot IDs		B4DX70 Q9H0C1	Q7Z6J9
PDB IDs
Enriched GO Terms of Interacting Partners?
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