ZMYND12 and MAD2L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZMYND12	MAD2L2
Description		zinc finger MYND-type containing 12	mitotic arrest deficient 2 like 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Chromosome Nucleolus Spindle Cytosol Zeta DNA Polymerase Complex Site Of Double-strand Break
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding JUN Kinase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Double-strand Break Repair Actin Filament Organization Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription By Competitive Promoter Binding Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Catabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Isotype Switching Positive Regulation Of Transcription, DNA-templated Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways			Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI
Drugs
Diseases
GWAS			Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		81 interacting genes: ABI2 ARHGAP8 ARMC8 ARNTL C1orf109 C1orf50 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM214B FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PPP1R32 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414	48 interacting genes: ADAM15 ADAM17 ADAM9 C20orf85 CAMK2B CDC20 CDH1 DEPDC5 ELK1 FAM217B FTO FZR1 GSC2 IKZF1 IKZF3 INCA1 KCTD9 KRT34 MAD2L1 MAD2L1BP MBD3L1 MYBPC2 PIGV PLAGL2 POLDIP2 PPM1B PRCC PRR5L PRRC2A RAB11FIP4 RBBP6 REL REV1 REV3L SFI1 SHLD1 TCF4 THAP6 TRIM27 TRIM54 TRIM7 YPEL3 YY1AP1 ZBED1 ZMYND12 ZNF511 ZNF558 ZNF655
Entrez ID		84217	10459
HPRD ID		15740	07246
Ensembl ID		ENSG00000066185	ENSG00000116670
Uniprot IDs		B4DX70 Q9H0C1	A0A024R4I4 Q9UI95
PDB IDs			3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5XPT 5XPU 6BC8 6BCD 6BI7 6K07 6K08 6KEA 6KTO 6M7A 6M7B 6NIF 6VE5 6WS0 6WS5 6WW9 6WWA 7L9P
Enriched GO Terms of Interacting Partners?
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