TSSK6 and MBP

Number of citations of the paper that reports this interaction (PubMedID 15870294)
35

Data Source:
BioGRID (enzymatic study)

		TSSK6	MBP
Description		testis specific serine kinase 6	myelin basic protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytosol Plasma Membrane Cell Surface Protein-containing Complex Internode Region Of Axon Neuronal Cell Body Myelin Sheath Compact Myelin Synapse Cell Periphery
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein-containing Complex Binding Protein Serine Kinase Activity	Protease Binding Protein Binding Calmodulin Binding Structural Constituent Of Myelin Sheath
	Biological Process	Protein Phosphorylation Peptidyl-serine Phosphorylation Sperm Chromatin Condensation Intracellular Signal Transduction	MAPK Cascade Immune Response Chemical Synaptic Transmission Central Nervous System Development Sensory Perception Of Sound Axon Ensheathment Response To Toxic Substance Substantia Nigra Development Positive Regulation Of Interleukin-6 Production Negative Regulation Of Heterotypic Cell-cell Adhesion Maintenance Of Blood-brain Barrier Myelination Membrane Organization Positive Regulation Of Metalloendopeptidase Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways			EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Percent liver fat ( 34128465) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 23974872)	Age-related macular degeneration (geographic atrophy) ( 22705344) Blood osmolality (transformed sodium) ( 28360221) Depression in smokers ( 30219690) Erythrocyte cadmium concentration in never smokers ( 27005419) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Verbal declarative memory ( 25648963)
Interacting Genes		13 interacting genes: APP H2AC20 H2AX H3C1 HSP90AB1 HSPA1A HSPA8 LYL1 MBP MPV17L2 OCEL1 SSBP1 TMEM38A	82 interacting genes: ABL1 ADRB2 APTX ATN1 ATXN1 AURKA BMP2K CCR1 CDK1 CDK12 CDK5 CDK7 CDK8 CDK9 CLK1 CTDSP1 CTDSPL DYRK1B HIPK2 HLA-DRA IKBKE ILK IRAK1 IRAK4 LIMK1 LIMK2 LRRK2 MAG MAP2K1 MAP3K1 MAP3K3 MAP3K5 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK15 MAPK3 MAPK8 MAPKAPK5 MELK MICU2 MKNK1 MMP7 NEK9 PAK1 PDGFRL PKN1 PLEKHF2 PLP1 PPP2R5C PRKACA PRKCA PRKCB PRKCD PRKCI PRKCZ PRKDC PRMT1 PRMT5 PTAFR PTPRA RAF1 RAN RPS6KA5 RTN4 SQSTM1 SRPK1 STK16 STK26 STK3 STK39 STK4 TBK1 TLK1 TLK2 TRAF6 TRPM7 TSC1 TSSK6 ULK1
Entrez ID		83983	4155
HPRD ID		15441	01158
Ensembl ID		ENSG00000178093	ENSG00000197971
Uniprot IDs		A0A024R7Q5 Q9BXA6	A0A024R384 P02686
PDB IDs			1BX2 1FV1 1HQR 1K2D 1QCL 1YMM 1ZGL
Enriched GO Terms of Interacting Partners?
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