GPR61 and ATP6V0B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPR61	ATP6V0B
Description		G protein-coupled receptor 61	ATPase H+ transporting V0 subunit b
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Receptor Complex	Lysosomal Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding	Transporter Activity Protein Binding Proton Transmembrane Transporter Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of CAMP-mediated Signaling	Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		20 interacting genes: APP ARL6IP6 ATP6V0B C4orf3 CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1	34 interacting genes: ADGRG3 ADRB2 APOD BPI CCL19 COL4A5 DAPK2 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM RPS26P15 SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 TTC39A VMA21 YWHAE YWHAG ZFYVE9
Entrez ID		83873	533
HPRD ID		06077	04759
Ensembl ID		ENSG00000156097	ENSG00000117410
Uniprot IDs		G4XH66 Q9BZJ8	E9PNL3 Q99437
PDB IDs			6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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