INHBE and PIP4K2C

		INHBE	PIP4K2C
Description		inhibin subunit beta E	phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Collagen-containing Extracellular Matrix	Nucleoplasm Autophagosome Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Organelle Extracellular Exosome
	Molecular Function	Cytokine Activity Hormone Activity Growth Factor Activity	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Identical Protein Binding
	Biological Process	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction	Regulation Of Autophagy Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly
Pathways		Glycoprotein hormones	Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus
Drugs			Fostamatinib
Diseases
GWAS		HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)	Rheumatoid arthritis ( 18794853)
Interacting Genes		6 interacting genes: FST GPR182 KRT73 NEMP1 PIP4K2C SDR9C7	6 interacting genes: APP BTK FBXO25 INHBE OGT PJA1
Entrez ID		83729	79837
HPRD ID		11047	15138
Ensembl ID		ENSG00000139269	ENSG00000166908
Uniprot IDs		P58166	B3KQV3 Q8TBX8
PDB IDs			2GK9
Enriched GO Terms of Interacting Partners?
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