PIP4K2C and INHBE

		PIP4K2C	INHBE
Description		phosphatidylinositol-5-phosphate 4-kinase type 2 gamma	inhibin subunit beta E
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Autophagosome Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Organelle Extracellular Exosome	Extracellular Space Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Identical Protein Binding	Cytokine Activity Hormone Activity Growth Factor Activity
	Biological Process	Regulation Of Autophagy Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction
Pathways		Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus	Glycoprotein hormones
Drugs		Fostamatinib
Diseases
GWAS		Rheumatoid arthritis ( 18794853)	HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)
Interacting Genes		6 interacting genes: APP BTK FBXO25 INHBE OGT PJA1	6 interacting genes: FST GPR182 KRT73 NEMP1 PIP4K2C SDR9C7
Entrez ID		79837	83729
HPRD ID		15138	11047
Ensembl ID		ENSG00000166908	ENSG00000139269
Uniprot IDs		B3KQV3 Q8TBX8	P58166
PDB IDs		2GK9
Enriched GO Terms of Interacting Partners?
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