CAPN3 and RNF167

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		CAPN3	RNF167
Description		calpain 3	ring finger protein 167
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleolus Cytoplasm Cytosol Plasma Membrane Myofibril Z Disc T-tubule Protein-containing Complex	Cytoplasm Endomembrane System Integral Component Of Membrane
	Molecular Function	Catalytic Activity Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Structural Constituent Of Muscle Sodium Ion Binding Titin Binding Ligase Regulator Activity Molecular Adaptor Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Proteolysis Apoptotic Process Muscle Organ Development Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Response To Muscle Activity Protein Catabolic Process Myofibril Assembly Protein Destabilization Negative Regulation Of Protein Sumoylation Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Sarcomere Organization Regulation Of Myoblast Differentiation Positive Regulation Of Proteolysis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Muscle Cell Cellular Homeostasis Regulation Of Catalytic Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Response To Calcium Ion Muscle Structure Development Protein-containing Complex Assembly G1 To G0 Transition Involved In Cell Differentiation Cellular Response To Calcium Ion Cellular Response To Salt Stress Protein Localization To Membrane Self Proteolysis Calcium-dependent Self Proteolysis	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle
Pathways		Degradation of the extracellular matrix
Drugs		L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal
Diseases
GWAS		Fibrinogen levels ( 28107422 26561523) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolite levels ( 23823483) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Triglyceride levels ( 32203549 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068 25961943 20686565)	Blood metabolite levels ( 24816252) Keratoconus ( 33649486) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		32 interacting genes: AMOT C1QTNF9 CCDC102B CEP76 CMYA5 CRYAB DYSF EXOC8 FLNC FNDC3B FXR1 GTPBP3 KANK2 MAP1LC3C MMP2 MYBPC1 MYBPH NECAB2 NTAQ1 OSGIN1 POMP PREPL PSMC3 PSMD1 RNF167 RUFY3 TFCP2 TRIM55 TRIM63 TTN UBE3A YWHAQ	18 interacting genes: ACTA1 AFG3L2 ATP2A1 CAPN3 MYH7 SLC22A18 SUMO1 TMEM97 TTN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2K UBE2N UBE2W
Entrez ID		825	26001
HPRD ID		00255	15261
Ensembl ID		ENSG00000092529	ENSG00000108523
Uniprot IDs		A0A0S2Z3E1 P20807	I3L0L6 Q9H6Y7
PDB IDs		1Y9V 4OKH 6BDT 6BGP 6BJD 6BKJ
Enriched GO Terms of Interacting Partners?
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