RNF167 and ATP2A1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		RNF167	ATP2A1
Description		ring finger protein 167	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endomembrane System Integral Component Of Membrane	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Platelet Dense Tubular Network Membrane Sarcoplasmic Reticulum Membrane Calcium Channel Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	P-type Calcium Transporter Activity Calcium Ion Binding Protein Binding ATP Binding P-type Ion Transporter Activity ATP Hydrolysis Activity Calcium-dependent ATPase Activity Protein Homodimerization Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle	Calcium Ion Transport Cellular Calcium Ion Homeostasis Apoptotic Mitochondrial Changes Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Ion Transmembrane Transport Response To Endoplasmic Reticulum Stress Positive Regulation Of Mitochondrial Calcium Ion Concentration Maintenance Of Mitochondrion Location Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Calcium Ion Import Calcium Ion Transmembrane Transport Relaxation Of Skeletal Muscle Positive Regulation Of Cardiac Muscle Cell Contraction Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Cardiac Conduction Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways			Pre-NOTCH Processing in Golgi Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs			Enflurane Desflurane Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Tetrafluoroaluminate Ion 2,5-di-tert-butylhydroquinone (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE
Diseases
GWAS		Blood metabolite levels ( 24816252) Keratoconus ( 33649486) Platelet count ( 32888494) Plateletcrit ( 32888494)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 19079260 26961502 28892062 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Brain morphology (MOSTest) ( 32665545) Cannabis use ( 30150663) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Hip circumference ( 31453325 25673412) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Type 2 diabetes ( 30297969) Waist circumference ( 31453325) Waist circumference variance ( 31453325) Weight ( 19079260)
Interacting Genes		18 interacting genes: ACTA1 AFG3L2 ATP2A1 CAPN3 MYH7 SLC22A18 SUMO1 TMEM97 TTN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2K UBE2N UBE2W	8 interacting genes: APPL1 CCR8 IRS1 IRS2 PLN RNF167 SLN TULP3
Entrez ID		26001	487
HPRD ID		15261	00157
Ensembl ID		ENSG00000108523	ENSG00000196296
Uniprot IDs		I3L0L6 Q9H6Y7	O14983 Q7Z675
PDB IDs
Enriched GO Terms of Interacting Partners?
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