SMC1A and RPGR

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		SMC1A	RPGR
Description		structural maintenance of chromosomes 1A	retinitis pigmentosa GTPase regulator
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Mitotic Spindle Pole	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	DNA Binding Chromatin Binding RNA Binding Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation DNA Repair Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Response To Radiation Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Response To DNA Damage Checkpoint Signaling Mitotic Spindle Assembly	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Mean corpuscular volume ( 32888494)
Interacting Genes		21 interacting genes: ALK AMOT ATM BLM BRCA1 ESR1 FGF14 MCM6 MCM7 MDC1 MET MSH2 MSH6 NDC80 NUMA1 POLA1 RAD21 RFC1 RPGR SMC3 SUMO2	19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE
Entrez ID		8243	6103
HPRD ID		02077	02425
Ensembl ID		ENSG00000072501	ENSG00000156313
Uniprot IDs		A0A384MR33 G8JLG1 Q14683 Q68EN4	Q92834
PDB IDs		6WG3 6WG4 6WG6 6WGE	4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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