RPGR and NUDT12

		RPGR	NUDT12
Description		retinitis pigmentosa GTPase regulator	nudix hydrolase 12
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Nucleus Cytoplasm Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	NAD+ Diphosphatase Activity Magnesium Ion Binding Protein Binding Zinc Ion Binding NADH Pyrophosphatase Activity RNA NAD-cap (NMN-forming) Hydrolase Activity Phosphodiesterase Decapping Endonuclease Activity
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly	MRNA Catabolic Process NADH Metabolic Process NADP Catabolic Process NAD Catabolic Process Circadian Regulation Of Gene Expression NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic NAD-cap Decapping Methylguanosine-cap Decapping
Pathways			Nicotinamide salvaging
Drugs
Diseases
GWAS			Academic attainment (English) ( 33594131) Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Blood protein levels ( 29875488) Body size at age 10 ( 32376654) Depression (quantitative trait) ( 23290196) Fasting glucose change ( 31263163) Gut microbiota (functional units) ( 27694959) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Longevity ( 30294719) Mitochondrial DNA levels ( 25240745) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Response to fenofibrate (total cholesterol levels) ( 27002377) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Triglyceride levels ( 32203549)
Interacting Genes		19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE	3 interacting genes: BLMH CAMK4 RPGR
Entrez ID		6103	83594
HPRD ID		02425	10123
Ensembl ID		ENSG00000156313	ENSG00000112874
Uniprot IDs		Q92834	Q9BQG2
PDB IDs		4JHN 4JHP 4QAM	6SCX
Enriched GO Terms of Interacting Partners?
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