DGCR6 and MBIP

Number of citations of the paper that reports this interaction (PubMedID 24722188)
63

Data Source:
BioGRID (two hybrid)

		DGCR6	MBIP
Description		DiGeorge syndrome critical region gene 6	MAP3K12 binding inhibitory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Extracellular Matrix	Nucleoplasm Nucleolus Cytosol
	Molecular Function	Molecular_function Protein Binding	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Animal Organ Morphogenesis	Positive Regulation Of Gene Expression Negative Regulation Of Catalytic Activity Histone H3 Acetylation Positive Regulation Of JNK Cascade
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Metabolite levels ( 23823483) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)	Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335)
Interacting Genes		66 interacting genes: ADAMTSL4 AGTRAP AKAP8L APP ARNT2 C1orf94 C3orf62 CBLL1 CBY2 CCDC33 CEP126 CTBP1 DEUP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 ESS2 FBF1 FH GOLGA2 GSE1 HGS HOMEZ IHO1 IKZF3 INIP KLHL12 KRTAP12-2 LZTS2 MBIP MEIS2 MEOX2 MIA2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NLA NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPRY2 SS18L1 TCF12 TCF4 TFIP11 TLE5 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446	47 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR1 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SHANK3 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TSC1 TXLNA TXLNB VPS28 VTA1 WDR5
Entrez ID		8214	51562
HPRD ID		03177	14368
Ensembl ID		ENSG00000183628	ENSG00000151332
Uniprot IDs		Q14129 X5D7D2	B2RCV0 Q9NS73
PDB IDs
Enriched GO Terms of Interacting Partners?
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