CLPP and NUTF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLPP	NUTF2
Description		caseinolytic mitochondrial matrix peptidase proteolytic subunit	nuclear transport factor 2
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex	Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytosol Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus MRNA Transport Protein Localization To Nuclear Pore Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways
Drugs		N-Formylmethionine
Diseases
GWAS			Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		19 interacting genes: ABI2 C14orf119 CHCHD3 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS STAT4 TNFSF9 TNPO3 TRIM54	55 interacting genes: BEND7 BRWD1 CAMK2G CANX CCDC106 CCDC150 CCDC158 CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B GLRX2 HMG20A HMG20B KHDC4 KPNB1 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NFAT5 NME1 NME4 NRIP3 NUP153 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SF3B3 SPATC1L SPRY4 TERF2 TEX35 THAP11 THAP3 TLE5 UBAP2 WWP2 YAF2 ZMAT2
Entrez ID		8192	10204
HPRD ID		03074	12050
Ensembl ID		ENSG00000125656	ENSG00000102898
Uniprot IDs		Q16740	A0A024R6Y2 P61970
PDB IDs		1TG6 6BBA 6DL7 6H23	1GY5
Enriched GO Terms of Interacting Partners?
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