CAMLG and PKHD1

Number of citations of the paper that reports this interaction (PubMedID 16243292)
12

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		CAMLG	PKHD1
Description		calcium modulating ligand	PKHD1 ciliary IPT domain containing fibrocystin/polyductin
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane GET Complex	Chromosome, Centromeric Region Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Cilium Integral Component Of Membrane Apical Plasma Membrane Anchored Component Of External Side Of Plasma Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm Extracellular Exosome Mitotic Spindle 9+0 Non-motile Cilium
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding	Protein Binding Signaling Receptor Activity
	Biological Process	B Cell Homeostasis Defense Response Signal Transduction Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane	Establishment Of Mitotic Spindle Orientation Kidney Development Regulation Of Cell-matrix Adhesion Epithelial Cell Morphogenesis Cellular Calcium Ion Homeostasis Positive Regulation Of Cell Population Proliferation Regulation Of Centrosome Duplication Regulation Of Cell-cell Adhesion Regulation Of Cell Adhesion Regulation Of TOR Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Homeostatic Process Negative Regulation Of Apoptotic Process Cell-cell Junction Organization Branching Morphogenesis Of An Epithelial Tube Positive Regulation Of Epithelial Cell Proliferation Negative Regulation Of Cellular Component Movement Establishment Of Centrosome Localization Negative Regulation Of Protein Kinase B Signaling Cilium Assembly Regulation Of ERK1 And ERK2 Cascade Regulation Of Establishment Of Planar Polarity Cell-cell Adhesion Negative Regulation Of Epithelial Cell Apoptotic Process Regulation Of Cholangiocyte Proliferation
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Cyclosporine
Diseases
GWAS		Height ( 18391951)	Adult body size ( 32376654) Alcohol use disorder ( 30940813) Body size at age 10 ( 32376654) Caffeine consumption from coffee ( 33287642) Caffeine consumption from tea ( 33287642) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Chronotype ( 30696823) Coffee consumption ( 31046077) Diastolic blood pressure ( 28135244 27841878) Epigenetic age acceleration in alcohol use disorder ( 31466081) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hematocrit ( 32888494) Hemoglobin ( 32888494) Intraocular pressure ( 29617998 24002674 29785010 31959993 30054594 29235454) Keratoconus ( 33649486) Longevity ( 30294719) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Post bronchodilator FEV1/FVC ratio ( 26634245) Prostate cancer ( 17903305) Red vs. brown/black hair color ( 30531825) Refractive error ( 32231278) Response to fenofibrate (triglyceride levels) ( 27002377) Tea consumption ( 31046077) Urinary sodium excretion ( 31409800) Waist circumference ( 19557197) Weight loss (gastric bypass surgery) ( 23633212)
Interacting Genes		22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB STT3B TMEM31 TNFRSF13B TXNDC12 VWC2	2 interacting genes: CAMLG PTGIS
Entrez ID		819	5314
HPRD ID		03073	05987
Ensembl ID		ENSG00000164615	ENSG00000170927
Uniprot IDs		P49069	P08F94
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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