CAMLG and KCNE4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CAMLG	KCNE4
Description		calcium modulating ligand	potassium voltage-gated channel subfamily E regulatory subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane GET Complex	Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding	Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	B Cell Homeostasis Defense Response Signal Transduction Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane	Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Phase 3 - rapid repolarisation Phase 2 - plateau phase
Drugs		Cyclosporine	Enflurane Promethazine Miconazole
Diseases
GWAS		Height ( 18391951)	Acute lymphoblastic leukemia (childhood) ( 19684603) Body mass index ( 20966902) Coronary artery disease in type 1 diabetes ( 32077919) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Fasting plasma glucose ( 32902719) Logical memory (delayed recall) in normal cognition ( 29274321) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Recurrent major depressive disorder x sex interaction ( 34099189) Reticulocyte count ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Waist circumference ( 20966902) Weight ( 28552196)
Interacting Genes		22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB STT3B TMEM31 TNFRSF13B TXNDC12 VWC2	10 interacting genes: CAMLG FLNA GET3 KCNA1 KCNQ1 OBSL1 PRKCA TCF7L2 TRDN TSNAX
Entrez ID		819	23704
HPRD ID		03073	09689
Ensembl ID		ENSG00000164615
Uniprot IDs		P49069	A5H1P5 Q8WWG9
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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