CYB5B and SLC16A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB5B	SLC16A2
Description		cytochrome b5 type B	solute carrier family 16 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Transporter Activity Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Symporter Activity Thyroid Hormone Transmembrane Transporter Activity
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress Electron Transport Chain Regulation Of Catalytic Activity	Cellular Amino Acid Metabolic Process Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		Phase I - Functionalization of compounds	Transport of organic anions
Drugs		Phenethyl Isothiocyanate	Pyruvic acid
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		55 interacting genes: AHNAK2 APP AQP6 B3GNT9 BIK BNIP3L BTNL9 CD33 CD79A CENPT CGRRF1 CLDN7 CLN8 COG8 CPLX4 CREB3 EBP ESRP2 FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PHAF1 PLPP4 REEP4 RETREG3 RPS2P45 SDHAF4 SLC10A6 SLC16A2 SLC39A9 SLC7A6OS STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA
Entrez ID		80777	6567
HPRD ID		13106	02106
Ensembl ID		ENSG00000103018	ENSG00000147100
Uniprot IDs		O43169	P36021
PDB IDs		3NER
Enriched GO Terms of Interacting Partners?
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