SLC16A2 and APOL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC16A2	APOL3
Description		solute carrier family 16 member 2	apolipoprotein L3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane	Extracellular Region Cytoplasm Membrane
	Molecular Function	Transporter Activity Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Symporter Activity Thyroid Hormone Transmembrane Transporter Activity	Lipid Transporter Activity Lipid Binding
	Biological Process	Cellular Amino Acid Metabolic Process Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Negative Regulation Of Neural Precursor Cell Proliferation	Lipid Transport Inflammatory Response Lipoprotein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Transport of organic anions
Drugs		Pyruvic acid
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Total intracranial volume ( 31530798)
Interacting Genes		38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA	28 interacting genes: ELOVL4 FATE1 FXYD6-FXYD2 GJA8 GJB1 GJB5 GJC1 GPR152 GPRC5D HAS3 IL7R LHFPL5 LINC00839 LRRC25 MFSD6 NCALD PMP22 RNF19B SGCB SLC16A2 SLC1A5 SLC7A14 STX1A TIMMDC1 TMEM167B TMEM237 TMEM52B TNFRSF10D
Entrez ID		6567	80833
HPRD ID		02106	06264
Ensembl ID		ENSG00000147100	ENSG00000128284
Uniprot IDs		P36021	A0A024R1G6 O95236
PDB IDs
Enriched GO Terms of Interacting Partners?
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