FLAD1 and PRTFDC1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
HPRD (two hybrid)

		FLAD1	PRTFDC1
Description		flavin adenine dinucleotide synthetase 1	phosphoribosyl transferase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix Cytosol Plasma Membrane
	Molecular Function	FMN Adenylyltransferase Activity Protein Binding ATP Binding Identical Protein Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	FAD Biosynthetic Process Riboflavin Metabolic Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process
Pathways		Vitamin B2 (riboflavin) metabolism
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732) Red blood cell count ( 32888494) Refractive error ( 32231278)	Body shape index ( 34021172) Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		21 interacting genes: ANXA7 APTX CDKN1A CLVS2 COPS3 CRABP2 DNM2 FXR1 GEMIN4 GRB7 L3MBTL3 NIF3L1 NUDT21 PRTFDC1 RCC1 REL SDCBP SMN1 TCF4 TK1 TRIM23	21 interacting genes: - CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 GPR158 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 RAB18 SPG21 STAT5A TCL1A TMEM14B VWA5A
Entrez ID		80308	56952
HPRD ID		17887	17917
Ensembl ID		ENSG00000160688	ENSG00000099256
Uniprot IDs		Q8NFF5	Q9NRG1
PDB IDs			2JBH
Enriched GO Terms of Interacting Partners?
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