CCDC6 and PPP4C

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CCDC6	PPP4C
Description		coiled-coil domain containing 6	protein phosphatase 4 catalytic subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding Identical Protein Binding	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Cytoskeleton Organization Biological_process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling
Pathways			Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		32 interacting genes: ATF2 ATF5 CCDC136 CCDC33 CENPQ CREB1 CSNK2A1 CYTH4 FBXW7 GAS8 LHX3 LRSAM1 LUZP4 MAPK3 MAPK7 MEOX2 MTUS2 PAX6 PIN1 PPP4C SH3RF1 SNAPC1 SORBS3 TFIP11 TRIM14 UBE2I WAC ZNF250 ZNF354C ZNF620 ZNF774 ZNF835	21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6
Entrez ID		8030	5531
HPRD ID		09064	03615
Ensembl ID		ENSG00000108091	ENSG00000149923
Uniprot IDs		Q05CP8 Q16204	A0A024R625 P60510
PDB IDs
Enriched GO Terms of Interacting Partners?
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