RABEP2 and FBXO25

Number of citations of the paper that reports this interaction (PubMedID 23940030)
8

Data Source:
BioGRID (enzymatic study)

		RABEP2	FBXO25
Description		rabaptin, RAB GTPase binding effector protein 2	F-box protein 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Centrosome Cytosol Ciliary Basal Body Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Nucleus Nucleolus Cytoplasm SCF Ubiquitin Ligase Complex
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity	Actin Binding Ubiquitin-protein Transferase Activity
	Biological Process	Endocytosis Signal Transduction Protein Transport Cell Projection Organization Regulation Of Catalytic Activity Regulation Of Cilium Assembly	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 31453325) Body mass index variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Cannabis use ( 30150663) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Obesity ( 23563607) Waist circumference adjusted for body mass index ( 34021172)	Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Nontraumatic osteonecrosis of the femoral head ( 32701715)
Interacting Genes		8 interacting genes: FBXO25 FRAT1 KAT8 MAP3K1 RAB4A RAB5A UBC VPS52	83 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DAXX DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		79874	26260
HPRD ID		17948	16439
Ensembl ID		ENSG00000177548	ENSG00000147364
Uniprot IDs		Q9H5N1	A0A024QZ88 Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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