FBXO25 and HP1BP3

Number of citations of the paper that reports this interaction (PubMedID 23940030)
8

Data Source:
BioGRID (enzymatic study)

		FBXO25	HP1BP3
Description		F-box protein 25	heterochromatin protein 1 binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus Cytoplasm SCF Ubiquitin Ligase Complex	Nucleosome Nucleus Chromosome Nuclear Speck
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity	DNA Binding Protein Binding Nucleosome Binding
	Biological Process	Protein Ubiquitination	Nucleosome Assembly Regulation Of Transcription, DNA-templated Regulation Of Cell Population Proliferation Heterochromatin Organization Cellular Response To Hypoxia Regulation Of Nucleus Size
Pathways
Drugs			Artenimol
Diseases
GWAS		Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Nontraumatic osteonecrosis of the femoral head ( 32701715)	Adventurousness ( 30643258) Cognitive decline rate in late mild cognitive impairment ( 26252872) Morning person ( 30696823) Physical activity (walking duration) ( 30531941)
Interacting Genes		83 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DAXX DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	7 interacting genes: APP FBXO25 MEOX2 MTDH OGT SLC26A4-AS1 SUMO2
Entrez ID		26260	50809
HPRD ID		16439	11026
Ensembl ID		ENSG00000147364	ENSG00000127483
Uniprot IDs		A0A024QZ88 Q8TCJ0	Q5SSJ5
PDB IDs			2RQP
Enriched GO Terms of Interacting Partners?
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