LRRK1 and ENKUR

Number of citations of the paper that reports this interaction (PubMedID 29513927)
16

Data Source:
BioGRID (pull down)

		LRRK1	ENKUR
Description		leucine rich repeat kinase 1	enkurin, TRPC channel interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Intracellular Membrane-bounded Organelle	Acrosomal Vesicle Sperm Principal Piece 9+0 Motile Cilium 9+2 Motile Cilium
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding Calmodulin Binding SH3 Domain Binding
	Biological Process	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction	Flagellated Sperm Motility Establishment Of Left/right Asymmetry
Pathways
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196) Systemic lupus erythematosus ( 33272962)
Interacting Genes		53 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SELENOS SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP TM2D3 VGLL4	7 interacting genes: CFAP45 GPR158 LRRK1 LRRK2 PIK3R1 PIK3R2 TRPC5
Entrez ID		79705	219670
HPRD ID		14319	12583
Ensembl ID		ENSG00000154237	ENSG00000151023
Uniprot IDs		Q38SD2	A0A087WUX1 Q8TC29
PDB IDs
Enriched GO Terms of Interacting Partners?
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