AIMP2 and RABEP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AIMP2	RABEP1
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	rabaptin, RAB GTPase binding effector protein 1
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GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Protein Binding Molecular Adaptor Activity	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Translation Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Regulation Of Catalytic Activity Membrane Fusion Protein Localization To Ciliary Membrane
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	TBC/RABGAPs
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252)	Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		105 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BRME1 BYSL C1orf216 CBY2 CCDC153 CEP126 CHD3 DARS1 DARS2 DEAF1 DISC1 DSN1 EPRS1 EPS8 EXOC8 FGB FHL3 FUBP1 GYS1 HSPA1A HSPA4 ICE1 KARS1 KDR KLC2 KRT31 KRT33B KRT34 KRT36 LMO2 LMO3 LNX1 LUC7L2 MAD1L1 MATR3 MCF2L MIR106A MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR15A MIR18A MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR34A MIR34B MIR34C MIR429 MIR451A MIR7-1 MIR7-2 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I MIS18A NDEL1 NECAB2 NTAQ1 PFDN6 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 RABEP1 SBK3 SLU7 SMURF2 SPATA18 TANK TCP11 TERF2IP TEX12 TFIP11 TRAF2 TRMT2A ZC3H12A ZGPAT	59 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 DDX3X ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		7965	9135
HPRD ID		02915	04684
Ensembl ID		ENSG00000106305	ENSG00000029725
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	B4DMM4 Q15276
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39	1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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