DDA1 and LNX2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
114

Data Source:
BioGRID (two hybrid)

		DDA1	LNX2
Description		DET1 and DDB1 associated 1	ligand of numb-protein X 2
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GO Annotations	Cellular Component	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Protein Ubiquitination
Pathways		Neddylation
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525) Systemic lupus erythematosus ( 23273568)	Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		6 interacting genes: AGTRAP CMTM5 CUL4B LNX2 PKNOX2 RDH10	90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581
Entrez ID		79016	222484
HPRD ID		15107	10042
Ensembl ID		ENSG00000130311	ENSG00000139517
Uniprot IDs		A0A024R7J7 Q9BW61	Q8N448
PDB IDs		6DSZ 6PAI 6Q0R 6Q0V 6Q0W 6SJ7 6UD7 6UE5	2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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