LNX2 and PPIH

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		LNX2	PPIH
Description		ligand of numb-protein X 2	peptidylprolyl isomerase H
Image
GO Annotations	Cellular Component		Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding
	Biological Process	Protein Ubiquitination	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Positive Regulation Of Viral Genome Replication Protein-containing Complex Assembly
Pathways			mRNA Splicing - Major Pathway
Drugs			Proline
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	15 interacting genes: BAG2 BPIFA1 DOK3 IPO13 KDM4A LNX1 LNX2 N4BP2L2 NIF3L1 PRPF18 PRPF31 PRPF4 SNU13 UBQLN2 XIAP
Entrez ID		222484	10465
HPRD ID		10042	12084
Ensembl ID		ENSG00000139517	ENSG00000171960
Uniprot IDs		Q8N448	O43447 Q6FH36
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22	1MZW 1QOI 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?