ZSCAN21 and GRAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZSCAN21	GRAP2
Description		zinc finger and SCAN domain containing 21	GRB2 related adaptor protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Ras Protein Signal Transduction Cell-cell Signaling
Pathways			Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 co-stimulation FLT3 Signaling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)
Interacting Genes		31 interacting genes: APP BRCA1 CAVIN1 CEP70 CLK2 DVL3 GRAP2 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 OGT PICK1 SCAND1 TRIM41 ZKSCAN4 ZKSCAN7 ZNF213 ZNF24 ZNF396 ZNF446 ZNF483 ZNF496 ZNF837 ZSCAN12 ZSCAN22 ZSCAN23 ZSCAN32	81 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RBX1 RIN3 RINT1 SH2D4A SHB SHC1 SLC25A17 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526 ZSCAN21
Entrez ID		7589	9402
HPRD ID		03162	05156
Ensembl ID		ENSG00000166529	ENSG00000100351
Uniprot IDs		Q9Y5A6	B7Z8E3 O75791 Q6FI14
PDB IDs			5GJH
Enriched GO Terms of Interacting Partners?
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