GRAP2 and PBLD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GRAP2	PBLD
Description		GRB2 related adaptor protein 2	phenazine biosynthesis like protein domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane	Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Molecular_function Protein Binding Isomerase Activity Identical Protein Binding
	Biological Process	Ras Protein Signal Transduction Cell-cell Signaling	Biosynthetic Process Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of SMAD Protein Signal Transduction
Pathways		Signaling by SCF-KIT Generation of second messenger molecules DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 co-stimulation FLT3 Signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971) Systemic lupus erythematosus ( 28714469)	Hip circumference adjusted for BMI ( 34021172) Optic disc parameters ( 20548946) Optic disc radius ( 31597446) Optic disc size ( 31809533) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Optic nerve measurement (disc area) ( 20395239) Vertical cup-disc ratio ( 20548946)
Interacting Genes		81 interacting genes: AR BAG4 BEND5 BLNK CBL CBLB CBY2 CCHCR1 CCNDBP1 CD28 COG6 CSF1R DNM2 DVL2 EGFR ERBB2 ERBB3 ERBB4 ETV5 FASLG GAB1 GAB2 GAB3 GAREM1 GATA1 GFAP GOLGA2 GRB2 HNRNPK IHO1 IKZF3 KHDRBS1 KHDRBS2 KIT KPRP KRT13 KRTAP1-3 KRTAP4-11 KRTAP4-12 LAT LATS2 LAX1 LCP2 LNX1 LNX2 MAGED1 MAP4K1 MKRN3 MOS MTUS2 PBLD PNMA1 PRKAA2 PRPH2 PRR35 RACK1 RAVER1 RBPMS RBX1 RIN3 RINT1 SH2D4A SHB SHC1 SLC25A17 SOS2 SPRY2 SSX2IP STAMBP TFIP11 TLE5 TRAF1 TSNAXIP1 USP8 WWP2 YWHAE ZBTB7B ZNF250 ZNF319 ZNF526 ZSCAN21	11 interacting genes: AMOT BEND7 CCDC184 EFHC2 GRAP2 LNX1 STRAP TCF4 TRIP13 VAC14 ZRANB1
Entrez ID		9402	64081
HPRD ID		05156	14366
Ensembl ID		ENSG00000100351	ENSG00000108187
Uniprot IDs		B7Z8E3 O75791 Q6FI14	A0A024QZK5 P30039
PDB IDs		5GJH
Enriched GO Terms of Interacting Partners?
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