VASP and GSN

Number of citations of the paper that reports this interaction (PubMedID 11093254)
16

Data Source:
HPRD (in vitro)

		VASP	GSN
Description		vasodilator stimulated phosphoprotein	gelsolin
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Exosome	Podosome Extracellular Region Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Sarcoplasm Actin Cap Cortical Actin Cytoskeleton Secretory Granule Lumen Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding	Actin Binding Calcium Ion Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol 3-kinase Catalytic Subunit Binding Myosin II Binding Actin Filament Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Protein Homotetramerization	Phagocytosis, Engulfment Central Nervous System Development Actin Polymerization Or Depolymerization Positive Regulation Of Gene Expression Striated Muscle Atrophy Extracellular Matrix Disassembly Cell Projection Assembly Actin Filament Polymerization Actin Filament Depolymerization Protein Destabilization Response To Muscle Stretch Sequestering Of Actin Monomers Actin Nucleation Negative Regulation Of Viral Entry Into Host Cell Actin Filament Severing Barbed-end Actin Filament Capping Positive Regulation Of Actin Nucleation Actin Filament Capping Relaxation Of Cardiac Muscle Cilium Assembly Regulation Of Podosome Assembly Cardiac Muscle Cell Contraction Actin Filament Reorganization Renal Protein Absorption Hepatocyte Apoptotic Process Positive Regulation Of Keratinocyte Apoptotic Process Regulation Of Establishment Of T Cell Polarity Regulation Of Plasma Membrane Raft Polarization Regulation Of Receptor Clustering Positive Regulation Of Protein Processing In Phagocytic Vesicle Amyloid Fibril Formation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions	Caspase-mediated cleavage of cytoskeletal proteins Neutrophil degranulation Sensory processing of sound by outer hair cells of the cochlea Amyloid fiber formation
Drugs			Zinc Latrunculin A Copper Zinc acetate
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)	Blood protein levels ( 30072576)
Interacting Genes		44 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP CDC42 CEP43 DMRTB1 DNMBP ENAH ERMAP EVL FAT1 FRS3 FYB1 GSN IQGAP1 LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	28 interacting genes: ACTA1 ACTB ACTG1 ACTN4 APP AR BCAR1 CASP3 CLIC5 CSK ERBB2 FHIT FN1 HSP90AA1 LIMK2 PIK3CG PLCG1 POLE3 PTK2B PXN RAB14 STK39 TNIK TOM1L1 TRIM32 VASP VCL VDAC1
Entrez ID		7408	2934
HPRD ID		03415	00674
Ensembl ID		ENSG00000125753	ENSG00000148180
Uniprot IDs		A0A024R0V4 P50552	A0A0A0MS51 A0A0A0MT01 A0A384MEF1 B7Z4U6 P06396
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW	1C0F 1C0G 1D4X 1DEJ 1EQY 1ESV 1H1V 1KCQ 1MDU 1NLV 1NM1 1NMD 1P8X 1P8Z 1SOL 1T44 1YAG 1YVN 2FF3 2FF6 2FH1 2FH2 2FH3 2FH4 3A5L 3A5M 3A5N 3A5O 3CI5 3CIP 3CJB 3CJC 3FFK 3FFN 3TU5 4PKG 4PKH 4PKI 4S10 4Z94 5DD2 5FAE 5FAF 5H3M 5H3N 5O2Z 5UBO 5ZZ0 6H1F 6JCO 6JEG 6JEH 6LJE 6LJF 6Q9R 6Q9Z 6QBF 6QW3
Enriched GO Terms of Interacting Partners?
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