VASP and FYB1

Number of citations of the paper that reports this interaction (PubMedID 10747096)
67

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VASP	FYB1
Description		vasodilator stimulated phosphoprotein	FYN binding protein 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Exosome	Nucleus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Protein-containing Complex
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding	Signaling Receptor Binding Protein Binding Lipid Binding Protein-containing Complex Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Protein Homotetramerization	Immune Response Integrin-mediated Signaling Pathway Biological_process T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions	Generation of second messenger molecules Generation of second messenger molecules Signal regulatory protein family interactions
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)	Sleep (1/2-day periodicity) ( 33075057)
Interacting Genes		44 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP CDC42 CEP43 DMRTB1 DNMBP ENAH ERMAP EVL FAT1 FRS3 FYB1 GSN IQGAP1 LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	15 interacting genes: BCAR1 CBL CBLB ENAH EVL FASLG FYN LCP2 NCK2 SH2D1A SKAP1 SKAP2 SRC VASP WAS
Entrez ID		7408	2533
HPRD ID		03415	04107
Ensembl ID		ENSG00000125753	ENSG00000082074
Uniprot IDs		A0A024R0V4 P50552	O15117
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW	1RI9 2GTJ 2GTO
Enriched GO Terms of Interacting Partners?
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