UVRAG and VPS18

Number of citations of the paper that reports this interaction (PubMedID 18552835)
325

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		UVRAG	VPS18
Description		UV radiation resistance associated	VPS18 core subunit of CORVET and HOPS complexes
Image			No pdb structure
GO Annotations	Cellular Component	Lytic Vacuole Autophagosome Membrane Chromosome, Centromeric Region Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Centrosome Midbody Phagocytic Vesicle	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Actin Filament AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Presynapse Glutamatergic Synapse
	Molecular Function	SNARE Binding Protein Binding SH3 Domain Binding	Actin Binding Protein Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Autophagy Spindle Organization Chromosome Segregation Centrosome Cycle Regulation Of Cytokinesis Receptor Catabolic Process SNARE Complex Assembly Viral Entry Into Host Cell Maintenance Of Golgi Location Regulation Of Protein Serine/threonine Kinase Activity Multivesicular Body Sorting Pathway Autophagosome Maturation Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Autophagosome Maturation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Lysosome Organization Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Viral Entry Into Host Cell Organelle Fusion Regulation Of Synaptic Vesicle Exocytosis
Pathways		Macroautophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Asthma ( 31619474) HDL cholesterol ( 30275531) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Mean spheric corpuscular volume ( 32888494) Stroke ( 32693751) Thumb osteoarthritis severity (hand Klsum) ( 33055079)	Hemoglobin ( 32888494) Malaria ( 31844061) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		8 interacting genes: CSNK1A1 MTOR OS9 VPS11 VPS16 VPS18 VPS33B ZRANB1	22 interacting genes: AKTIP CLCN3 COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B RAB7A RILP SHANK3 STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		7405	57617
HPRD ID		03929	09776
Ensembl ID		ENSG00000198382	ENSG00000104142
Uniprot IDs		Q9P2Y5	A0A024R9R3 Q9P253
PDB IDs		7BL1
Enriched GO Terms of Interacting Partners?
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