UBE2H and RNF128

Number of citations of the paper that reports this interaction (PubMedID 12705856)
109

Data Source:
BioGRID (pull down)

		UBE2H	RNF128
Description		ubiquitin conjugating enzyme E2 H	ring finger protein 128
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GO Annotations	Cellular Component	Nucleus Cytosol	Cytoplasm Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Protein Stability Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163 31451708) Lymphocyte counts ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Response to antidepressants and depression ( 27622933) White blood cell count ( 32888494)	Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)
Interacting Genes		67 interacting genes: BRAP BYSL CBLC CD99 CDK2 DTX3 DTX3L DZIP3 EPS15 GOLGA2 H2AC18 HBP1 HDAC6 JADE1 LNX2 LRSAM1 MAEA MARCHF1 MARCHF10 MARCHF2 MARCHF4 MARCHF8 MKRN3 NEURL1 NHLRC1 POLL POLM PRKN PSME3 RAG1 RELA RNF10 RNF103 RNF113B RNF114 RNF128 RNF133 RNF139 RNF144A RNF146 RNF166 RNF185 RNF186 RNF2 RNF34 RNF38 RNF4 RNF6 STAM2 TLE5 TRAIP TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM28 TRIM36 TRIM37 TRIM5 TRIM56 TRIM69 UBA1 UBASH3B UBOX5 UBR2 UBR3	16 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 SNX17 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T UBQLN2
Entrez ID		7328	79589
HPRD ID		03052	02340
Ensembl ID		ENSG00000186591	ENSG00000133135
Uniprot IDs		A0A3B3IU20 A4D1L5 P62256	Q8TEB7
PDB IDs		2Z5D	3ICU
Enriched GO Terms of Interacting Partners?
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