TSG101 and DMAP1

Number of citations of the paper that reports this interaction (PubMedID 10888872)
296

Data Source:
HPRD (in vivo, two hybrid)

		TSG101	DMAP1
Description		tumor susceptibility 101	DNA methyltransferase 1 associated protein 1
Image
GO Annotations	Cellular Component	ESCRT I Complex Nucleolus Cytoplasm Endosome Early Endosome Late Endosome Multivesicular Body Microtubule Organizing Center Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Late Endosome Membrane Extracellular Exosome Flemming Body	Swr1 Complex Nucleus Nucleoplasm Replication Fork Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Nuclear Receptor Coactivator Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Binding Protein-containing Complex Binding Virion Binding Calcium-dependent Protein Binding	Transcription Corepressor Activity Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Protein Monoubiquitination Extracellular Transport Cell Cycle Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Cell Population Proliferation Endosome To Lysosome Transport Protein Transport Macroautophagy Keratinocyte Differentiation Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Positive Regulation Of Transcription, DNA-templated Viral Budding Cell Division Regulation Of Cell Cycle Autophagosome Maturation Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly Positive Regulation Of Viral Budding Via Host ESCRT Complex Exosomal Secretion Positive Regulation Of Ubiquitin-dependent Endocytosis	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Methylation Regulation Of Growth Positive Regulation Of Protein Import Into Nucleus Histone Exchange Histone H4 Acetylation Histone H2A Acetylation Response To Ethanol Negative Regulation Of Transcription, DNA-templated
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	HATs acetylate histones
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		122 interacting genes: AATF ADRB2 AJUBA AKAP9 AR ARRDC1 BAG4 BCAS3 BCR BIRC2 CAGE1 CBY1 CCDC88B CCHCR1 CCND3 CDKN1A CDKN2D CDS2 CEP55 CEP63 CNOT7 DAXX DMAP1 DMRTB1 DNMT1 DZIP3 EP300 FAM110A FAM9B GGA1 GGA3 GMCL1 GOLM1 HAUS1 HCK HGS HSH2D INCA1 IQGAP1 ITSN1 JUN KIAA1328 KIF5A KIFC3 KLK5 KLK6 KRT13 KRT15 KRT16 KRT18 KRT31 KRT34 KRT35 KRT75 LCN2 LENG8 LNX1 LRSAM1 MDM2 MGRN1 MKRN3 MTA3 MZB1 NR3C1 OGT PDCD6IP PDLIM7 PIAS1 PKNOX2 PPFIBP2 PPP1R13B PRDM16 PRSS50 QKI RAD18 RASL10B RBPMS RNF111 RNF126 RNF41 ROCK1 SCAMP3 SCARA5 SCGB3A1 SCNN1A SH3GLB2 SHANK3 SNAPIN SNF8 SNX32 STK11 SYCE1 TAX1BP1 TEX11 TFF1 TFIP11 THRB THRSP TNIP1 TNIP2 TNNT3 TOM1L1 TP53 TRAIP TRIM23 TRIM35 TRIM46 TRIM54 TRIM74 TRIML2 UBA52 UBC USHBP1 VPS11 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D WASHC1 ZWINT	39 interacting genes: ARFIP2 BFSP2 C1orf216 CCHCR1 CDCA7L DAXX DNMT1 EXOC8 GAS8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 OGT PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1
Entrez ID		7251	55929
HPRD ID		03229	05465
Ensembl ID		ENSG00000074319	ENSG00000178028
Uniprot IDs		Q99816	Q9NPF5
PDB IDs		1KPP 1KPQ 1M4P 1M4Q 1S1Q 2F0R 3IV1 3OBQ 3OBS 3OBU 3OBX 3P9G 3P9H 4EJE 4YC1 4ZNY 5VKG 6VME	3HM5 4IEJ
Enriched GO Terms of Interacting Partners?
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