TRIP6 and MVP

Number of citations of the paper that reports this interaction (PubMedID 24722188)
63

Data Source:
BioGRID (two hybrid)

		TRIP6	MVP
Description		thyroid hormone receptor interactor 6	major vault protein
Image
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Interleukin-1 Receptor Binding Protein Binding Kinase Binding Metal Ion Binding Thyroid Hormone Receptor Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Cell Migration Chordate Embryonic Development Focal Adhesion Assembly Positive Regulation Of NIK/NF-kappaB Signaling	Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Serum alkaline phosphatase levels ( 33547301)	Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		165 interacting genes: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP23 ATP5PO ATXN1 AXIN1 BAG3 BCAR1 BEX2 BYSL C11orf87 CATSPER1 CBLC CCDC120 CCDC187 CCDC24 CCL5 CEP57L1 CNTF CREB5 CRYBA4 CTAG2 DHX37 DMRT3 DTX2 EFHC1 EPDR1 ERBB2 EXOC3-AS1 FAM124B FAM222B FARS2 FAS FASLG FHL3 FOXD4L1 FRS3 GAD1 GATA1 GDPD5 GFI1B GLIS3 GNAI2 GNE GPS2 GSE1 HCK HLA-DPB1 HOXA1 HOXA9 HOXB9 HOXC8 HYKK IL16 ILF3 INCA1 IP6K3 IQCN ITGB4 KCTD9 KIF1A KIR2DL4 KLK15 KPRP KRTAP26-1 LMO2 LNX1 LPAR2 MAPKBP1 MEMO1 METTL17 MIEN1 MIIP MISP MSRB3 MVP NCK2 NEDD9 NEU4 NOL4L-DT NR1D2 NSMF NUP210 ODF1 OIP5 OTUB2 OTX1 PATZ1 PDGFRB PDLIM4 PER1 PIGS PIN1 PLEKHN1 POM121 POM121L4P PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PTPN14 PXN RAD23A RANBP3L RELN RERE RFX3 RHOA RHOQ RNF213 RNF214 SAXO1 SCAND1 SCRIB SETDB1 SHISA6 SIK3 SLC15A3 SLC25A6 SMAD1 SMG9 SNAI1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TBC1D22B TCAF1 TEKT4 TENT5C THRB TIE1 TLE5 TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TSGA10IP TSSK3 TTC23 TTLL10 TXN2 TXNDC5 USP2 VASN VCL WT1-AS YPEL3 ZBP1 ZIC1 ZNF541 ZNF580 ZNF581 ZNF688 ZNF785	68 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DNAH5 DTX2 EPHX2 ESR1 FMR1 FNDC3B FXR1 FXR2 GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2
Entrez ID		7205	9961
HPRD ID		04242	05475
Ensembl ID		ENSG00000087077	ENSG00000013364
Uniprot IDs		Q15654	Q14764 X5D2M8 X5D7K9 X5DNU0
PDB IDs		1X61 2DLO	1Y7X
Enriched GO Terms of Interacting Partners?
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