MVP and PSTPIP1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
63

Data Source:
BioGRID (two hybrid)

		MVP	PSTPIP1
Description		major vault protein	proline-serine-threonine phosphatase interacting protein 1
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen	Uropod Cytoplasm Cytosol Actin Filament Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding	Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Actin Filament Polymerization Innate Immune Response
Pathways		Neutrophil degranulation	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 34021172)	Hip circumference adjusted for BMI ( 34021172) Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		68 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DNAH5 DTX2 EPHX2 ESR1 FMR1 FNDC3B FXR1 FXR2 GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2	65 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MFGE8 MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688
Entrez ID		9961	9051
HPRD ID		05475	05891
Ensembl ID		ENSG00000013364	ENSG00000140368
Uniprot IDs		Q14764 X5D2M8 X5D7K9 X5DNU0	A0A0S2Z5P3 O43586
PDB IDs		1Y7X	2DIL
Enriched GO Terms of Interacting Partners?
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