TNNI3 and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 11904166)
4

Data Source:
HPRD (in vitro)

		TNNI3	TNNT1
Description		troponin I3, cardiac type	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex Sarcomere Cardiac Myofibril Cardiac Troponin Complex	Cytosol Troponin Complex
	Molecular Function	Actin Binding Protein Binding Calcium Channel Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Troponin C Binding Troponin T Binding Metal Ion Binding Calcium-dependent Protein Binding Actin Filament Binding	Protein Binding Tropomyosin Binding Troponin T Binding
	Biological Process	Vasculogenesis Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Skeletal Muscle Contraction Cellular Calcium Ion Homeostasis Muscle Contraction Regulation Of Smooth Muscle Contraction Heart Development Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Negative Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction
Pathways		Striated Muscle Contraction Ion homeostasis	Striated Muscle Contraction
Drugs		N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases
GWAS		Monocyte count ( 32888494) Platelet count ( 32888494)	Height ( 31562340)
Interacting Genes		19 interacting genes: ACTA1 HSPB2 LYST MST1 PAPPA PKD2 PKD2L1 PRKCA PSMC5 RASSF10 RCAN3 SOX4 TNNC1 TNNC2 TNNI3K TNNT1 TNNT2 TRIM55 TRIM63	69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		7137	7138
HPRD ID		11769	01841
Ensembl ID		ENSG00000129991	ENSG00000105048
Uniprot IDs		P19429 Q6FGX2	P13805
PDB IDs		1J1D 1J1E 1LXF 1MXL 1OZS 2KGB 2KRD 2L1R 2MZP 2N7L 4Y99 5VLN 5W88 5WCL 6KN7 6KN8 6MV3 7JGI
Enriched GO Terms of Interacting Partners?
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