TNNT1 and OSM

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TNNT1	OSM
Description		troponin T1, slow skeletal type	oncostatin M
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Cytokine Activity Oncostatin-M Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Positive Regulation Of Acute Inflammatory Response Immune Response Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Interleukin-17 Production Positive Regulation Of Peptidyl-serine Phosphorylation Oncostatin-M-mediated Signaling Pathway Regulation Of Growth Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of MAPK Cascade Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Inflammatory Response Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Striated Muscle Contraction	Interleukin-4 and Interleukin-13 signaling IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Height ( 31562340)	Coronary artery disease ( 29212778 33020668) Delirium ( 29631748) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Myocardial infarction ( 33532862) Nephropathy ( 21399633) Suicidal ideation ( 30145303) Tonsillectomy ( 27941131)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	13 interacting genes: APP COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 IL6ST LIFR NF2 OSMR TNNT1 ZNF410
Entrez ID		7138	5008
HPRD ID		01841	01300
Ensembl ID		ENSG00000105048	ENSG00000099985
Uniprot IDs		P13805	B5MCX1 P13725
PDB IDs			1EVS
Enriched GO Terms of Interacting Partners?
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