TSPAN4 and ITGA6

Number of citations of the paper that reports this interaction (PubMedID 9360996)
23

Data Source:
HPRD (in vivo)

		TSPAN4	ITGA6
Description		tetraspanin 4	integrin subunit alpha 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Vesicle	Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Filopodium Integrin Alpha6-beta4 Complex
	Molecular Function	Antigen Binding Integrin Binding Protein Binding	Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding Laminin Binding Protein-containing Complex Binding Cadherin Binding Metal Ion Binding
	Biological Process	Protein-containing Complex Assembly	Cell-substrate Junction Assembly Integrin-mediated Signaling Pathway Ectodermal Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Positive Regulation Of Cell Migration Cell-substrate Adhesion Nail Development Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Skin Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Organic Cyclic Compound Cell-cell Adhesion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Assembly of collagen fibrils and other multimeric structures Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Laminin interactions Syndecan interactions Type I hemidesmosome assembly
Drugs
Diseases
GWAS		Falling risk ( 32999390)	Alzheimer's disease biomarkers ( 23419831) Blood protein levels ( 28240269) Diabetic kidney disease ( 26305897) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Food allergy ( 29030101) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Prostate cancer ( 31562322 19767753)
Interacting Genes		49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3	22 interacting genes: ADAM9 APP BIN1 CALM1 CANX CD151 CD36 CD63 CD82 COL17A1 GIPC1 GRB2 ITGB1 ITGB4 LGALS3BP PCSK5 PLEC PRKCD PXN RABIF RPSA TSPAN4
Entrez ID		7106	3655
HPRD ID		04033	00945
Ensembl ID		ENSG00000214063	ENSG00000091409
Uniprot IDs		A0A024RCE1 A8MVV6 O14817	P23229
PDB IDs
Enriched GO Terms of Interacting Partners?
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