TSPAN4 and TMEM106A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSPAN4	TMEM106A
Description		tetraspanin 4	transmembrane protein 106A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Vesicle	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Antigen Binding Integrin Binding Protein Binding	Molecular_function Protein Binding
	Biological Process	Protein-containing Complex Assembly	Biological_process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production CD80 Biosynthetic Process CD86 Biosynthetic Process Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process
Pathways
Drugs
Diseases
GWAS		Falling risk ( 32999390)	Blood protein levels ( 30072576)
Interacting Genes		49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3	13 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM106C TMEM107 TMEM128 TMEM86B TNMD TSPAN4
Entrez ID		7106	113277
HPRD ID		04033	11315
Ensembl ID		ENSG00000214063	ENSG00000184988
Uniprot IDs		A0A024RCE1 A8MVV6 O14817	B7Z779 Q96A25
PDB IDs
Enriched GO Terms of Interacting Partners?
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