TDO2 and MOB3C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

		TDO2	MOB3C
Description		tryptophan 2,3-dioxygenase	MOB kinase activator 3C
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Protein Binding Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin	Positive Regulation Of Protein Phosphorylation Signal Transduction
Pathways		Tryptophan catabolism
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)	Chronic kidney disease ( 30226566) Hypertension ( 30226566)
Interacting Genes		20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26	18 interacting genes: APP CMTM3 FAM118A FBXO7 IKZF4 KANK2 KRT40 LATS1 LATS2 NT5C2 PCYT1A PICK1 PTPN21 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10
Entrez ID		6999	148932
HPRD ID		01847	17584
Ensembl ID		ENSG00000151790	ENSG00000142961
Uniprot IDs		P48775	Q70IA8 X6R3L3
PDB IDs		4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6UD5 6VBN
Enriched GO Terms of Interacting Partners?
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